.Attribute Medication, Posted online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and epidemiologic analyses uncovered that an unfamiliar reassortant popular descent of the Oropouche virus, which has been spreading in the western side Amazon region of South america for regarding a decade, is linked with the latest human episodes in between 2022 and also 2024.